Research shows that Advil® has a favorable safety profile*

As with any medication, there are risks associated with the use of ibuprofen. However, research has shown that ibuprofen at OTC doses has a favorable overall safety profile. A recent review confirmed that at OTC doses, ibuprofen has a low incidence of serious GI events and minimal risk of causing renal and associated cardiovascular events, among others.1

Also, when used as directed ibuprofen 400 mg has a favorable GI safety profile. Higher Rx doses may heighten the risk of GI injury1-3 and may be associated with an increased number of cardiovascular events.1