FACT: FACT:

Advil® demonstrates a low risk of hepatic injury1,2

Liver Liver

ADVIL DEMONSTRATES A LOW RISK OF ACUTE LIVER DAMAGE

Liver safety data from systematic reviews, population-based studies, and spontaneous reporting databases indicate that there is a low risk of acute liver damage associated with ibuprofen use.3-6

The hepatic safety profile of ibuprofen extends to overdose situations.7,8

When compared with acetaminophen, the incidence of ibuprofen-induced liver injury is very low1,2,9

  • The hepatotoxicity of acetaminophen is well documented and dose-related2
  • When high toxic doses of acetaminophen were taken, irreversible liver damage was observed9

SAFETY INFORMATION FOR YOUR PATIENTS

The Advil Drug Facts recommend that patients with liver cirrhosis should consult a doctor before use.